(S)-1-{(RP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine is an organic compound commonly referred to as (S)-iPr-PTTL.
Nature:
The compound is an organic phosphorus compound with a white crystalline solid in appearance. Its chemical formula is C32H35FeFP2 and its relative molecular mass is 570.25g/mol.
Use:
(S)-iPr-PTTL is a chiral phosphine ligand, which is widely used in metal-catalyzed reactions in organic synthesis, especially in transition metal-catalyzed asymmetric synthesis. It is usually used to catalyze asymmetric hydrogenation, hydrogenation-sulfurization and other reactions, and can effectively catalyze the enantioselective reaction.
Preparation Method:
The synthesis of (S)-iPr-PTTL is usually achieved by chemical synthesis. The specific step is that an appropriate amount of (S)-(-)-diphenylphosphine platinum dichloride is reacted with silylated ferrocene, and then the reaction, crystallization, purification and other steps are carried out.
Safety Information:
No special security issues were reported. However, as a chemical substance, it is still necessary to operate with caution and in accordance with laboratory safety practices. Reasonable storage and disposal are based on the specific physicochemical properties of the compound.